Orthobiologics are biologically derived materials and preparations used in musculoskeletal and regenerative medicine. Common orthobiologic technologies include platelet-rich plasma (PRP), platelet-rich fibrin (PRF), bone marrow aspirate concentrate (BMAC) and adipose tissue-derived preparations such as stromal vascular fraction (SVF). STR Biotechnologies is a medical device manufacturer focused on point-of-care regenerative medicine and orthobiologic preparation technologies.

SVF isolation efficiency is not determined by cell concentration alone. A reliable Stromal Vascular Fraction (SVF) preparation should be evaluated using multiple parameters, including total cell yield, cell viability, tissue processing efficiency, cellular composition and reproducibility. Both enzymatic and mechanical isolation methods can produce viable SVF preparations, but their cellular characteristics and processing mechanisms may differ.

Platelet-derived extracellular vesicles (pEVs) are membrane-bound particles released by platelets constitutively and in response to activation. Studying these vesicles requires more than simply detecting nanoscale particles. A scientifically robust extracellular-vesicle workflow typically involves several stages: Platelet Source → Pre-Analytical Control → Platelet Activation → EV Release → Separation → Particle Analysis → Morphological Analysis → Molecular Characterization → Cellular-Origin V