S&M PRF+ Technology
Injectable Platelet Rich Fibrin System
Thanks to the smooth inner tube wall, platelets are exposed to less centrifugation stress, thus prolonging the coagulation process. Experience PRP and i-PRF technologies without anticoagulants with our S&M PRF+ system.
What is i-PRF?
i-PRF is a type of PRF in liquid form obtained through a special low-centrifugation protocol.
Thanks to its injectable structure, it distributes more homogeneously and integrates more easily into the tissue.
Mirror-like, flawless interior surface design.
Anticoagulant-free STR PRF+ Tubes help preserve the natural biological properties of platelets thanks to their micro-polished inner surface technology. This innovative system, which enables the production of PRP and i-PRF, offers a reliable and user-friendly solution for regenerative medicine applications.
Try How Easy to Use
The resulting injectable PRF (i-PRF) maintains its fluid consistency suitable for application for approximately 30 minutes, reaching an average biological fraction volume of 3–4 ml. With its rapid preparation process, ease of use, and anticoagulant-free nature, STR PRF+ Tube is a reliable solution developed for modern regenerative medicine applications.
Centrifuge Protocol for i-PRF
400G (1500 RPM) 3 minutes
ON THE SURFACE OF DENTAL IMPLANT
PRF
COATING TECHNOLOGY
Biological support at the implant-tissue interface with autologous fibrin matrix
PRF Implant Coating Technology involves applying patient-derived, platelet and fibrin-rich autologous material to the dental implant surface using a special preparation protocol. The aim is to create a biological fibrin matrix on the threaded surface of the implant, supporting early implant-tissue interaction.
PRF COATING TECHNOLOGY IN 4 STEPS
Place the dental implant into the PRF tube.
The sterile dental implant is placed in a small, sealed preparation tube designed for the procedure.
Add the previously prepared Buffy Coat mixture to the tube.
The pre-prepared Buffy Coat fraction, rich in platelets and cellular components, is transferred into the tube in a controlled manner.
Perform hard spin centrifugation.
The implant and autologous biological material are centrifuged together at validated times and RCF values.
1900g, 5 minutes
PRF-coated implants are ready for use.
The centrifugation process aims to obtain a biological coating consisting of fibrin and platelet components on the implant surface. The prepared implant is transported to the application area without delay.
BIOLOGICAL MECHANISM OF ACTION
Biological Fibrin Interface on Implant Surface
The PRF coating protocol aims to create an autologous fibrin network on the micro and macro surfaces of the implant. This structure creates a microenvironment that can:
Retain platelets on the implant surface,
Formation of a fibrin matrix,
Controlled release of growth factors,
Create a temporary biological scaffold for cellular adhesion,
Support early biological processes at the implant-bone interface.
Scientific studies report that PRF application can contribute to early implant stability.
BIOLOGICAL SURFACE SUPPORT
ADVANTAGES OF PRF IMPLANT COATING TECHNOLOGY
Autologous biological content
It uses fibrin and platelet components obtained
from the patient's own blood.
Closed preparation process
With its appropriate kit design, it helps control the risk of contamination during the transfer and centrifugation stages.
Surface coating approach
It aims for the fibrin matrix to make direct contact with the threaded surface of the implant.
Standardized protocol
The tube, centrifuge, and preparation components can be verified together.
Early biological support
It can help support the early healing phase after implant placement.
Practical clinical application
It supports performing the coating procedure immediately before implant placement.
COMPARISON OF STANDARD IMPLANTS AND PRF-COATED IMPLANTS
Değerlendirme Standart implant PRF kaplama yaklaşımı
Yüzey Titanyum implant yüzeyi Otolog fibrin matriksiyle temas eden yüzey
Biyolojik arayüz Kan pıhtısı doğal olarak oluşur Fibrin ve trombosit içeriğinin yüzeyde yoğunlaştırılması hedeflenir
Hücresel etkileşim Fizyolojik iyileşme süreci Erken hücresel etkileşimin desteklenmesi amaçlanır
Büyüme faktörleri Cerrahi alandaki doğal düzey Lokal biyolojik mediyatör desteği hedeflenir
Uygulama Standart implant prosedürü Ek tüp, transfer ve santrifüj protokolü gerektirir
SCIENTIFIC EVIDENCE
Scientific studies on PRF:
In a split-mouth randomized clinical trial, implants treated with PRF showed statistically significant higher stability values at weeks 2, 4, and 6 compared to the control group. However, the differences were not at the level of a “60% increase” (Tabrizi et al.).
In another clinical study, the mean ISQ value at week 4 was reported as 69.3 in implants treated with PRF and 64.5 in the control group (Öncü et al.).
Systematic reviews and meta-analyses indicate that PRF can particularly support early or secondary implant stability, but heterogeneity exists among protocols (2023 meta-analysis, 2024 meta-analysis).
Animal studies are investigating the potential of liquid PRF coating applied directly to the implant surface on osseointegration (Liquid PRF implant coating study).
